Metilarsonat reduktaza
Metilarsonat reduktaza (EC 1.20.4.2, MMA(V) reduktaza) je enzim sa sistematskim imenom glutation:metilarsonat oksidoreduktaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
Metilarsonat reduktaza | |||||||||
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Identifikatori | |||||||||
EC broj | 1.20.4.2 | ||||||||
CAS broj | 254889-62-8 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- metilarsonat + 2 glutation metilarsonit + glutation disulfid + H2O
Produkt, Me-As(OH)2 (metilarsenitna kiselina), se biološki metiluje posredstvom enzima EC 2.1.1.137, arsenit metiltransferaze, čime se formira kakodilinska kiselinu.
Reference
urediLiteratura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
uredi- Methylarsonate+reductase на US National Library of Medicine Medical Subject Headings (MeSH)