Metilkvercetagetin 6-O-metiltransferaza
Metilkvercetagetin 6-O-metiltransferaza (EC 2.1.1.84, flavonolna 6-O-metiltransferaza, flavonolna 6-metiltransferaza, 6-OMT, S-adenozil-L-metionin:3',4',5,6-tetrahidroksi-3,7-dimetoksiflavon 6-O-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:5,6,3',4'-tetrahidroksi-3,7-dimetoksiflavon 6-O-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Metilkvercetagetin 6-O-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.84 | ||||||||
| CAS broj | 97089-68-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- S-adenozil-L-metionin + 5,6,3',4'-tetrahidroksi-3,7-dimetoksiflavon S-adenozil-L-homocistein + 5,3',4'-trihidroksi-3,6,7-trimetoksiflavon
Enzims iz Chrysosplenium americanum takođe metiliše 3,7,3'-trimetilkvercetagetin u 6-poziciji.
Reference
uredi- ^ De Luca, V. & Ibrahim, R.K. (1985). „Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4′-O-methyltransferases”. Arch. Biochem. Biophys. 238: 596—605. PMID 3994393.
- ^ De Luca, V. & Ibrahim, R.K. (1985). „Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. II. Substrate interaction and product inhibition studies of flavonol 3-, 6-, and 4′-O-methyltransferases”. Arch. Biochem. Biophys. 238: 606—618. PMID 3994394.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
uredi- Methylquercetagetin+6-O-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
