Mikofenolna kiselina acil-glukuronidna esteraza
Mikofenolna kiselina acil-glukuronidna esteraza (EC 3.1.1.93, mikofenolna kiselina acil-glukuronidna deglukuronidaza, AcMPAG deglukuronidaza) je enzim sa sistematskim imenom mikofenolna kiselina O-acil-glukuronid-estar hidrolaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Mikofenolna kiselina acil-glukuronidna esteraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.1.93 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- mikofenolna kiselina O-acil-glukuronid + H2O mikofenolat + D-glukuronat
Ovaj jetreni enzim deglukuronidiše mikofenolna kiselina O-acil-glukuronid, koja je metabolit imunosupresantnog leka mikofenolata.
Reference
urediLiteratura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
uredi- Mycophenolic+acid+acyl-glucuronide+esterase na US National Library of Medicine Medical Subject Headings (MeSH)
