NADPH dehidrogenaza (hinon)
NADPH dehidrogenaza (hinon) (EC 1.6.5.10, redukovani nikotinamid adenin dinukleotid fosfat (hinon) dehidrogenaza, NADPH oksidaza, NADPH2 dehidrogenaza (hinon)) je enzim sa sistematskim imenom NADPH:(hinon-akceptor) oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| NADPH dehidrogenaza (hinon) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.6.5.10 | ||||||||
| CAS broj | 37256-37-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Ovaj enzim je flavoprotein. Enzim iz Escherichia coli je specifičan za NADPH i najaktivniji je na hinonskim derivatima.
Reference
uredi- ^ Koli, A.K., Yearby, C., Scott, W. and Donaldson, K.O. (1969). „Purification and properties of three separate menadione reductases from hog liver”. J. Biol. Chem. 244: 621—629. PMID 4388793.
- ^ Hayashi, M., Hasegawa, K., Oguni, Y. and Unemoto, T. (1990). „Characterization of FMN-dependent NADH-quinone reductase induced by menadione in Escherichia coli”. Biochim. Biophys. Acta. 1035: 230—236. PMID 2118386.
- ^ Hayashi, M., Ohzeki, H., Shimada, H. and Unemoto, T. (1996). „NADPH-specific quinone reductase is induced by 2-methylene-4-butyrolactone in Escherichia coli”. Biochim. Biophys. Acta. 1273: 165—170. PMID 8611590.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
uredi- NADPH+dehydrogenase+(quinone) na US National Library of Medicine Medical Subject Headings (MeSH)
