Pikornain 2A
Pikornain 2A (EC 3.4.22.29, pikornavirusna endopeptidaza 2A, poliovirusna proteaza 2A, rinovirusna proteaza 2A, 2A proteaza, 2A proteinaza, proteaza 2A, proteinaza 2Apro, pikornaviralna 2A proteinaza, Y-G proteinaza 2A, poliovirusna proteinaza 2A, poliovirusna proteaza 2Apro, pikornaviralna 2A proteinaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Pikornain 2A | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.22.29 | ||||||||
| CAS broj | 103406-62-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Selektivno razlaganje Tyr-Gly veze u pilornavirusnom poliproteinu
Ovaj enzim izražavaju entero-, rino-, afto- i kardiovirusi.
Reference
uredi- ^ Bazan, J.F. & Fletterick, R.J. (1988). „Viral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implications”. Proc. Natl Acad. Sci. USA. 85: 7872—7876. PMID 3186696.
- ^ König, H. & Rosenwirth, B. (1988). „Purification and partial characterization of poliovirus protease 2A by means of a functional assay”. J. Virol. 62: 1243—1250. PMID 2831385.
- ^ Kräusslich, H.-G. and Wimmer, E. (1988). „Viral proteinases”. Annu. Rev. Biochem. 57: 701—754. PMID 3052288.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
uredi- Picornain+2A na US National Library of Medicine Medical Subject Headings (MeSH)
