Prokolagenska N-endopeptidaza
Prokolagenska N-endopeptidaza (EC 3.4.24.14, prokolagen N-terminalna peptidaza, prokolagenska aminopeptidaza, aminoprokolagenska peptidaza, aminoterminalna prokolagenska peptidaza, prokolagenska aminoterminalna proteaza, prokolagenska N-terminalna proteinaza, tip I/II prokolagenska N-proteinaza, tip III prokolagen) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Prokolagenska N-endopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.14 | ||||||||
| CAS broj | 68651-94-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Razlaganje N-propeptidnog lanca kolagena alfa1(I) na Pro-Gln, kao i alfa1(II) i alfa2(I) na Ala-Gln
Ovaj enzim deluje na propeptide tipa I i II kolagena.
Reference
uredi- ^ Kohn, L.D., Iserky, C., Zupnik, J., Lenaers, A., Lee, G. and Lapiére, C.M. (1974). „Calf tendon procollagen peptidase: its purification and endopeptidase mode of action”. Proc. Natl. Acad. Sci. USA. 71: 40—44. PMID 4204204.
- ^ Hojima, Y., McKenzie, J., van der Rest, M. and Prockop, D.J. (1989). „Type I procollagen N-proteinase from chick embryo tendons. Purification of a new 500-kDa form of the enzyme and identification of the catalytically active polypeptides”. J. Biol. Chem. 264: 11336—11345. PMID 2500439.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
uredi- Procollagen+N-endopeptidase na US National Library of Medicine Medical Subject Headings (MeSH)
