Putrescin aminotransferaza
Putrescin aminotransferaza (EC 2.6.1.82, putrescin-alfa-ketoglutarat transaminaza, YgjG, putrescin:alfa-ketoglutarat aminotransferaza, PAT, putrescin:2-oksoglutarat aminotransferaza, putrescinska transaminaza) je enzim sa sistematskim imenom butan-1,4-diamin:2-oksoglutarat aminotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Putrescin aminotransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.82 | ||||||||
| CAS broj | 98982-73-1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- putrescin + 2-oksoglutarat 1-pirolidin + L-glutamat +H2O (sveukupna reakcija)
- (1a) putrescin + 2-oksoglutarat 4-aminobutanal + L-glutamat
- (1b) 4-aminobutanal 1-pirolidin +H2O (spontana reakcija)
Ovaj enzim je piridoksal-fosfatni protein.
Reference
uredi- ^ Prieto-Santos, M.I., Martin-Checa, J., Balaña-Fouce, R. and Garrido-Pertierra, A. (1986). „A pathway for putrescine catabolism in Escherichia coli”. Biochim. Biophys. Acta. 880: 242—244. PMID 3510672.
- ^ Samsonova, N.N., Smirnov, S.V., Novikova, A.E. and Ptitsyn, L.R. (2005). „Identification of Escherichia coli K12 YdcW protein as a γ-aminobutyraldehyde dehydrogenase”. FEBS Lett. 579: 4107—4112. PMID 16023116.
- ^ Samsonova, N.N., Smirnov, S.V., Altman, I.B. and Ptitsyn, L.R. (2003). „Molecular cloning and characterization of Escherichia coli K12 ygjG gene”. BMC Microbiol. 3: 2—2. PMID 12617754.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
uredi- Putrescine+aminotransferase na US National Library of Medicine Medical Subject Headings (MeSH)
