Tripsin
Tripsin (EC 3.4.21.4, alfa-tripsin, beta-tripsin, kokunaza, parenzim, parenzimol, triptar, tripur, pseudotripsin, tripcelim, sperm receptorska hidrolaza) je enzim.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Tripsin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.4.21.4 | ||||||||
| CAS broj | 2594141 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Preferentno odvajanje: Arg-, Lys-
Jednolančani polipeptid goveđeg beta-tripsina se formira iz tripsinogena razlaganjem jedne peptidne veze.
Reference uredi
- ^ Huber, R. & Bode, W. (1978). „Structural basis of the activation and action of trypsin”. Acc. Chem. Res. 11: 114—122.
- ^ Walsh, K.A. (1970). „Trypsinogens and trypsins of various species”. Methods Enzymol. 19: 41—63.
- ^ Read, R.J., Brayer, G.D., Jurásek, L. and James, M.N.G. (1984). „Critical evaluation of comparative model building of Streptomyces griseus trypsin”. Biochemistry. 23: 6570—6575. PMID 6442164.
- ^ Fiedler, F. (1987). „Effects of secondary interactions on the kinetics of peptide and peptide ester hydrolysis by tissue kallikrein and trypsin”. Eur. J. Biochem. 163: 303—312. PMID 3643848.
- ^ Fletcher, T.S., Alhadeff, M., Craik, C.S. and Largman, C. (1987). „Isolation and characterization of a cDNA encoding rat cationic trypsinogen”. Biochemistry. 26: 3081—3086. PMID 3112218.
- ^ Polgár, L. (1987). „Structure and function of serine proteases”. Ur.: Neuberger, A. and Brocklehurst, K. New Comprehensive Biochemistry: Hydrolytic Enzymes. 16. Amsterdam: Elsevier. str. 159—200.
- ^ Tani, T., Kawashima, I., Mita, K. and Takiguchi, Y. (1990). „Nucleotide sequence of the human pancreatic trypsinogen III cDNA”. Nucleic Acids Res. 18: 1631—1631. PMID 2326201.
Literatura uredi
- Polgár, L. (1987). „Structure and function of serine proteases”. Ur.: Neuberger, A. and Brocklehurst, K. New Comprehensive Biochemistry: Hydrolytic Enzymes. 16. Amsterdam: Elsevier. str. 159—200.
