2-Metil-5-hidroksitriptamin

2-Metil-5-hidroksitriptamin
IUPAC ime
	3-(2-aminoethyl)-2-methyl-1H-indol-5-ol
Identifikatori
CAS broj	78263-90-8
PubChem	CID 1574
IUPHAR/BPS	218
ChemSpider	1518
KEGG	C13665
ChEMBL	CHEMBL266591
Hemijski podaci
Formula	C11H14N2O
Molarna masa	190.242 g/mol
	SMILES Oc1cc2c(cc1)nc(c2CCN)C; ;
	InChI InChI=1S/C11H14N2O/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7/h2-3,6,13-14H,4-5,12H2,1H3 ; Key:WYWNEDARFVJQSG-UHFFFAOYSA-N ;

2-Metil-5-hidroksitriptamin (2-Metilserotonin, 2-Metil-5-HT) je triptaminski derivat koji je blisko srodan neurotransmiteru serotonin. On deluje kao umereno selektivan agonist 5-HT₃ receptora.^[1]^[2]^[3]

Vidi još

^ Elz S, Zimmermann H, Rehse K (1993). „Selectivity of sterically fixed tryptamine and 5-methoxytryptamine derivatives for serotonin receptor subtypes, II: Structure-activity relationships and in vitro pharmacology of N-alkyl- and N,N-dialkyl-3- indolylbicyclo-[2.2.1]-heptane-2-amines.”. Arch Pharm (Weinheim). 326 (11): 893—899. PMID 8274071. doi:10.1002/ardp.19933261110.
^ Craig DA, Eglen RM, Walsh LK, Perkins LA, Whiting RL, Clarke DE (1990). „5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum.”. Naunyn Schmiedebergs Arch Pharmacol. 342 (1): 9—16. PMID 2402303.
^ Glennon RA, Dukat M, Westkaemper RB (01. 01. 2000). „Serotonin Receptor Subtypes and Ligands”. American College of Neurophyscopharmacology. Приступљено 11. 04. 2008.

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