Fenilacetaldoksimska dehidrataza
Fenilacetaldoksimska dehidrataza (EC 4.99.1.7, PAOx dehidrataza, arilacetaldoksimska dehidrataza, OxdB, (Z)-fenilacetaldehid-oksimska hidrolijaza) je enzim sa sistematskim imenom (Z)-fenilacetaldehid-oksim hidrolijaza (formira fenilacetonitril).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Fenilacetaldoksimska dehidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.99.1.7 | ||||||||
| CAS broj | 203210-76-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- (Z)-fenilacetaldehid oksim fenilacetonitril + H2O
Enzim iz Bacillus sp. OxB-1 sadrži protohem IX.
Reference
уреди- ^ Kato, Y., Nakamura, K., Sakiyama, H., Mayhew, S.G. and Asano, Y. (2000). „Novel heme-containing lyase, phenylacetaldoxime dehydratase from Bacillus sp. strain OxB-1: purification, characterization, and molecular cloning of the gene”. Biochemistry. 39: 800—809. PMID 10651646.
- ^ Kobayashi, K., Yoshioka, S., Kato, Y., Asano, Y. and Aono, S. (2005). „Regulation of aldoxime dehydratase activity by redox-dependent change in the coordination structure of the aldoxime-heme complex”. J. Biol. Chem. 280: 5486—5490. PMID 15596434.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Phenylacetaldoxime+dehydratase на US National Library of Medicine Medical Subject Headings (MeSH)
