Feredoksin hidrogenaza
Feredoksin hidrogenaza (EC 1.12.7.2, H2 oksidaciona hidrogenaza, H2 formirajuća hidrogenaza (nespecifična), bidirekciona hidrogenaza, vodonična lijaza (nespecifična), hidrogenaza (feredoksin), hidrogenaza I, hidrogenaza II) je enzim sa sistematskim imenom vodonik:feredoksin oksidoreduktaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
Feredoksin hidrogenaza | |||||||||
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Identifikatori | |||||||||
EC broj | 1.12.7.2 | ||||||||
CAS broj | 2603212 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- H2 + 2 oksidovani feredoksin 2 redukovani feredoksin + 2 H+
Ovaj enzim sadrži gvožđe-sumporne klustere. Enzimi iz nekih izvora sadrže nikal.
Reference
уреди- ^ Shug, A.L., Wilson, P.W., Green, D.E. and Mahler, H.R. (1954). „The role of molybdenum and flavin in hydrogenase”. J. Am. Chem. Soc. 76: 3355—3356.
- ^ Tagawa, K. & Arnon, D.I. (1962). „Ferredoxin as electron carriers in photosynthesis and in the bioogical production and consumption of hydrogen gas”. Nature (Lond.). 195: 537—543.
- ^ Valentine, R.C., Mortenson, L.E. and Carnahan, J.E. (1963). „The hydrogenase system of Clostridium pasteurianum”. J. Biol. Chem. 238: 1141—1144.
- ^ Zumft, W.G. & Mortenson, L.E. (1975). „The nitrogen-fixing complex of bacteria”. Biochim. Biophys. Acta. 416: 1—52. PMID 164247.
- ^ Adams, M.W.W. (1990). „The structure and mechanism of iron-hydrogenases”. Biochim. Biophys. Acta. 1020: 115—145. PMID 2173950.
- ^ Peters, J.W., Lanzilotta, W.N., Lemon, B.J. and Seefeldt, L.C. (1998). „X-ray crystal structure of the Fe-only hydrogenase (Cpl) from Clostridium pasteurianum to 1.8 Angstrom resolution”. Science. 282: 1853—1858. PMID 9836629.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Ferredoxin+hydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)