Fosfatidilholin 12-monooksigenaza
Fosfatidilholin 12-monooksigenaza (EC 1.14.13.26, ricinoleinska kiselina sintaza, oleatna Delta12-hidroksilaza, oleatna Delta12-monooksigenaza) je enzim sa sistematskim imenom 1-acil-2-oleoil-sn-glicero-3-fosfoholin,NADH:kiseonik oksidoreduktaza (12-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Fosfatidilholin 12-monooksigenaza | |||||||||
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Identifikatori | |||||||||
EC broj | 1.14.13.26 | ||||||||
CAS broj | 77950-95-9 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- 1-acil-2-oleoil-sn-glicero-3-fosfoholin + NADH + H+ + O2 1-acil-2-[(S)-12-hidroksioleoil]-sn-glicero-3-fosfoholin + NAD+ + H2O
Reference
уреди- ^ Galliard, T. & Stumpf, P.K. (1966). „Fat metabolism in higher plants. 30. Enzymatic synthesis of ricinoleic acid by a microsomal preparation from developing Ricinus communis seeds”. J. Biol. Chem. 241: 5806—5812. PMID 4289003.
- ^ Moreau, R.A. & Stumpf, P.K. (1981). „Recent studies of the enzymic-synthesis of ricinoleic acid by developing castor beans”. Plant Physiol. 67: 672—676. PMID 16661734.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Phosphatidylcholine+12-monooxygenase на US National Library of Medicine Medical Subject Headings (MeSH)