Galaktozilgalaktozilglukozilkeramidaza
Galaktozilgalaktozilglukozilkeramidaza (EC 3.2.1.47, triheksozil keramid galaktozidaza, keramidna triheksozidaza, keramidtriheksozidna alfa-galaktozidaza, triheksozilkeramidna alfa-galaktozidaza, keramidtriheksozidaza) je enzim sa sistematskim imenom alfa-D-galaktozil-(1->4)-beta-D-galaktozil-(1->4)-beta-D-glukozil-(1<->1)-keramid galaktohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Galaktozilgalaktozilglukozilkeramidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.2.1.47 | ||||||||
| CAS broj | 2601625 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- alfa-D-galaktozil-(1->4)-beta-D-galaktozil-(1->4)-beta-D-glukozil-(1<->1)-keramid + H2O D-galaktoza + beta-D-galaktozil-(1->4)-beta-D-glukozil-(1<->1)-keramid
Reference
уреди- ^ Brady, R.O., Gal, A.E., Bradley, R.M. and Matensson, E. (1967). „The metabolism of ceramide trihexosides. I. Purification and properties of an enzyme that cleaves the terminal galactose molecule of galactosylgalactosylglucosylceramide”. J. Biol. Chem. 242: 1021—1026. PMID 6020428.
- ^ Mapes, C.A. & Sweeley, C.C. (1972). „Substrate specificity of ceramide trihexosidase”. FEBS Lett. 25: 279—281. PMID 11946769.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Galactosylgalactosylglucosylceramidase на US National Library of Medicine Medical Subject Headings (MeSH)
