N4-(beta-N-acetilglukozaminil)-L-asparaginaza
N4-(beta-N-acetilglukozaminil)-L-asparaginaza (EC 3.5.1.26, aspartilglukozilaminska deaspartilaza, aspartilglukozilaminaza, aspartilglukozaminidaza, aspartilglikozilaminska amidohidrolaza, N-aspartil-beta-glukozaminidaza, glukozilamidaza, beta-aspartilglukozilaminska amidohidrolaza, 4-N-(beta-N-acetil-D-glukozaminil)-L-asparaginska amidohidrolaza) je enzim sa sistematskim imenom N4-(beta-N-acetil-D-glukozaminil)-L-asparagin amidohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
N4-(beta-N-acetilglukozaminil)-L-asparaginaza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.5.1.26 | ||||||||
CAS broj | 9075-24-5 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- N4-(beta-N-acetil-D-glukozaminil)-L-asparagin + H2O N-acetil-beta-D-glukozaminilamin + L-aspartat
Ovaj enzim deluje samo na asparagin-oligosaharide koji sadrže jednu aminokiselinu.
Reference
уреди- ^ Kohno, M. & Yamashina, I. (1972). „Purification and properties of 4-L-aspartylglycosylamine amidohydrolase from hog kidney”. Biochim. Biophys. Acta. 258: 600—617. PMID 5010303.
- ^ Mahadevan, S. & Tappel, A.L. (1967). „β-Aspartylglucosylamine amido hydrolase of rat liver and kidney”. J. Biol. Chem. 242: 4568—4576. PMID 6061403.
- ^ Tarentino, A.L. & Maley, F. (1969). „The purification and properties of a β-aspartyl N-acetylglucosylamine amidohydrolase from hen oviduct”. Arch. Biochem. Biophys. 130: 295—303. PMID 5778645.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- N4-(beta-N-acetylglucosaminyl)-L-asparaginase на US National Library of Medicine Medical Subject Headings (MeSH)