Nukleotidna difosfataza
Nukleotid difosfataza (EC 3.6.1.9, nukleotidna pirofosfataza, nukleotid-šećerna pirofosfataza) je enzim sa sistematskim imenom dinukleotid nukleotidohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
Nukleotid difosfataza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.6.1.9 | ||||||||
CAS broj | 9032-64-8 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- dinukleotid + H2O 2 mononukleotida
Supstrati su: NAD+, NADP+, FAD, KoA, kao i ATP i ADP.
Reference
уреди- ^ Jacobson, J.B. & Kaplan, N.O. (1957). „A reduced pyridine nucleotide pyrophosphatase”. J. Biol. Chem. 226: 427—437. PMID 13428775.
- ^ Kornberg, A. & Pricer, W.E. (1950). „Nucleotide pyrophosphatase”. J. Biol. Chem. 182: 763—778.
- ^ Kumar, S.A., Rao, N.A. and Vaidyanathan, C.S. (1965). „Nucleotidases in plants. I. Partial purification and properties of the enzyme hydrolyzing flavine adenine dinucleotide from mung bean seedlings (Phaseolus radiatus)”. Arch. Biochem. Biophys. 111: 646—652. PMID 5862212.
- ^ Swartz, M.N., Kaplan, N.O. and Lamborg, M.F. (1958). „A' "heat-activated" diphosphopyridine nucleotide pyrophosphatase from Proteus vulgaris”. J. Biol. Chem. 232: 1051—1063. PMID 13549486.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Nucleotide+diphosphatase на US National Library of Medicine Medical Subject Headings (MeSH)