Sirohidrohlorna ferohelataza
Sirohidrohlorna ferohelataza (EC 4.99.1.4, CysG, Met8P, SirB, sirohidrohlorinska fero-lijaza) je enzim sa sistematskim imenom siroheme fero-lijaza (formira sirohidrohlorin).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Sirohidrohlorna ferohelataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.99.1.4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- sirohem + 2 H+ sirohidrohlorin + Fe2+
Ovaj enzim katalizuje treći korak formiranja sirohema iz uroporfirinogena III.
Reference
уреди- ^ Schubert, H.L., Raux, E., Brindley, A.A., Leech, H.K., Wilson, K.S., Hill, C.P. and Warren, M.J. (2002). „The structure of Saccharomyces cerevisiae Met8p, a bifunctional dehydrogenase and ferrochelatase”. EMBO J. 21: 2068—2075. PMID 11980703.
- ^ Warren, M.J., Raux, E., Schubert, H.L. and Escalante-Semerena, J.C. (2002). „The biosynthesis of adenosylcobalamin (vitamin B12)”. Nat. Prod. Rep. 19: 390—412. PMID 12195810.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Sirohydrochlorin+ferrochelatase на US National Library of Medicine Medical Subject Headings (MeSH)
