1,5-anhidro-D-fruktoza dehidrataza
1,5-Anhidro-D-fruktoza dehidrataza (EC 4.2.1.111, 1,5-anhidro-D-fruktoza 4-dehidrataza, 1,5-anhidro-D-fruktoza hidrolijaza, 1,5-anhidro-D-arabino-heks-2-uloza dehidrataza, AFDH, AF dehidrataza, 1,5-anhidro-D-fruktoza hidrolijaza) je enzim sa sistematskim imenom 1,5-anhidro-D-fruktoza hidrolijaza (formira askopiron-M).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 1,5-Anhidro-D-fruktoza dehidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.111 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- 1,5-anhidro-D-fruktoza 1,5-anhidro-4-dezoksi-D-glicero-heks-3-en-2-uloza + H2O
Ovaj enzim katalizuje jedan korak u anhidrofruktoznom putu, koji dovodi do degradacije glikogena i skroba preko 1,5-anhidro-D-fruktoze.
Reference уреди
- ^ Yu, S., Refdahl, C. and Lundt, I. (2004). „Enzymatic description of the anhydrofructose pathway of glycogen degradation; I. Identification and purification of anhydrofructose dehydratase, ascopyrone tautomerase and α-1,4-glucan lyase in the fungus Anthracobia melaloma”. Biochim. Biophys. Acta. 1672: 120—129. PMID 15110094.
- ^ Yu, S. & Fiskesund, R. (2006). „The anhydrofructose pathway and its possible role in stress response and signaling”. Biochim. Biophys. Acta. 1760: 1314—1322. PMID 16822618.
- ^ Yu, S. (2005). „Enzymatic description of the anhydrofructose pathway of glycogen degradation. II. Gene identification and characterization of the reactions catalyzed by aldos-2-ulose dehydratase that converts 1,5-anhydro-D-fructose to microthecin with ascopyrone M as the intermediate”. Biochim. Biophys. Acta. 1723: 63—73. PMID 15716041.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- 1,5-anhydro-D-fructose+dehydratase на US National Library of Medicine Medical Subject Headings (MeSH)
