Diizopropilna fluorofosfataza
Diizopropilna fluorofosfataza (EC 3.1.8.2, DFPaza, tabunaza, somanaza, organofosforno kiselinska anhidrolaza, organofosfat kiselinska anhidraza, OPA anhidraza, diizopropilfosfofluoridaza, dialkilfluorofosfataza, diizopropil fosforofluoridatna hidrolaza, izopropilfosforofluoridaza, diizopropilfluorofosfonatna dehalogenaza) je enzim sa sistematskim imenom diizopropil-fluorofosfat fluorohidrolaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Diizopropilna fluorofosfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.8.2 | ||||||||
| CAS broj | 9032-18-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- diizopropil fluorofosfat + H2O diizopropil fosfat + fluorid
Ovaj enzim deluje na fosforne anhidridne veze (poput fosfor-halida i fosfor-cijanida) u organofosfornim jedinjenjima (uključujući 'nervne gasove').
Reference
уреди- ^ Augustinsson, K.-B. & Heimburger, G. (1954). „Enzymatic hydrolysis of organophosphorus compounds. I. Occurrence of enzymes hydrolysing dimethyl-amido-ethoxy-phosphoryl cyanide (Tabun)”. Acta Chem. Scand. 8: 753—761.
- ^ Augustinsson, K.-B. & Heimburger, G. (1954). „Enzymatic hydrolysis of organophosphorus compounds. II. Analysis of reaction products in experiments with Tabun and some properties of blood plasma tabunase”. Acta Chem. Scand. 8: 762—767.
- ^ Augustinsson, K.-B. & Heimburger, G. (1954). „Enzymatic hydrolysis of organophosphorus compounds. IV. Specificity studies”. Acta Chem. Scand. 8: 1533—1541.
- ^ Cohen, J.A. & Warringa, M.G.P.J. (1957). „Purification and properties of dialkylfluorophosphatase”. Biochim. Biophys. Acta. 26: 29—39. PMID 13479457.
- ^ Mounter, L.A. (1960). „Enzymic hydrolysis of organophosphorus compounds”. Ур.: Boyer, P.D., Lardy, H.; Myrb; auml; ck, K. The Enzymes. 4 (2nd изд.). New York: Academic Press. стр. 541—550.
- ^ Reiner, E., Aldridge, W.N. and Hoskin, C.G., ур. (1989). Enzymes Hydrolysing Organophosphorus Compounds. Chichester, UK: Ellis Horwood. стр. —.
Литература
уреди- Reiner, E., Aldridge, W.N. and Hoskin, C.G., ур. (1989). Enzymes Hydrolysing Organophosphorus Compounds. Chichester, UK: Ellis Horwood. стр. —.
- Mounter, L.A. (1960). „Enzymic hydrolysis of organophosphorus compounds”. Ур.: Boyer, P.D., Lardy, H.; Myrb; auml; ck, K. The Enzymes. 4 (2nd изд.). New York: Academic Press. стр. 541—550.
Spoljašnje veze
уреди- Diisopropyl-fluorophosphatase на US National Library of Medicine Medical Subject Headings (MeSH)
