Glutamatna karboksipeptidaza
Glutamatna karboksipeptidaza (EC 3.4.17.11, karboksipeptidaza G, karboksipeptidaza G1, karboksipeptidaza G2, glutamilna karboksipeptidaza, N-pteroil-L-glutamat hidrolaza) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glutamatna karboksipeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.17.11 | ||||||||
| CAS broj | 9074-87-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Odvajanje C-terminalnih glutamatnih ostataka sa širokog opsega N-acilacovanih grupa, uključujući peptidil, aminoacil, benzoil, benziloksikarbonil, folil i pteroil grupe
Ovaj cinkov enzim proizvodi Pseudomonadaceae, Flavobakterija sp. i Acinetobacter sp.
Reference
уреди- ^ Goldman, P. & Levy, C.C. (1967). „Carboxypeptidase G: purification and properties”. Proc. Natl Acad. Sci. USA. 58: 1299—1306. PMID 5237864.
- ^ McCullogh, J.L., Chabner, B.A. and Bertino, J.R. (1971). „Purification and properties of carboxypeptidase G1”. J. Biol. Chem. 246: 7207—7213. PMID 5129727.
- ^ Albrecht, A.M., Boldizar, E. and Hutchinson, D.J. (1978). „Carboxypeptidase displaying differential velocity in hydrolysis of methotrexate, 5-methyltetrahydrofolic acid, and leucovorin”. J. Bacteriol. 134: 506—513. PMID 26657.
- ^ Sherwood, R.F., Melton, R.G. and Alwan, S.A. (1985). „Purification and properties of carboxypeptidase G2 from Pseudomonas sp. strain RS-16”. Eur. J. Biochem. 148: 447—453. PMID 3838935.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Glutamate+carboxypeptidase на US National Library of Medicine Medical Subject Headings (MeSH)
