Horizmatna lijaza
Horizmatna lijaza (EC 4.1.3.40, CL, CPL, UbiC) je enzim sa sistematskim imenom horizmat piruvat-lijaza (formira 4-hidroksibenzoat).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Horizmatna lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifikatori | |||||||||
| EC broj | 4.1.3.40 | ||||||||
| CAS broj | 157482-18-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj enzim katalizuje prvi korak biosinteze ubihinona u bakteriji Escherichia coli i drugim Gram-negativim bakterijama.
Reference уреди
- ^ Nichols, B.P. & Green, J.M. (1992). „Cloning and sequencing of Escherichia coli ubiC and purification of chorismate lyase”. J. Bacteriol. 174: 5309—5316. PMID 1644758.
- ^ Siebert, M., Severin, K. and Heide, L. (1994). „Formation of 4-hydroxybenzoate in Escherichia coli: characterization of the ubiC gene and its encoded enzyme chorismate pyruvate-lyase”. Microbiology. 140: 897—904. PMID 8012607.
- ^ Meganathan, R. (2001). „Ubiquinone biosynthesis in microorganisms”. FEMS Microbiol. Lett. 203: 131—139. PMID 11583838.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Chorismate+lyase на US National Library of Medicine Medical Subject Headings (MeSH)
