Karnozinska sintaza
Karnozinska sintaza (EC 6.3.2.11, karnozinska sintetaza, karnozin-anserinska sintetaza, homokarnozin-karnozinska sintetaza, karnozin-homokarnozinska sintetaza, L-histidin:beta-alanin ligaza (formira AMP)) je enzim sa sistematskim imenom L-histidin:beta-alanin ligaza (formira ADP).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Karnozinska sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.3.2.11 | ||||||||
| CAS broj | 9023-61-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ova enzim formira ADP.
Reference уреди
- ^ Kalyankar, G.D. & Meister, A. (1959). „Enzymatic synthesis of carnosine and related β-alanyl and γ-aminobutyryl peptides”. J. Biol. Chem. 234: 3210—3218. PMID 14404206.
- ^ Stenesh, J.J. & Winnick, T. (1960). „Carnosine-anserine synthetase of muscle. 4. Partial purification of the enzyme and further studies of β-alanyl peptide synthesis”. Biochem. J. 77: 575—581. PMID 16748858.
- ^ Crush, K.G. (1970). „Carnosine and related substances in animal tissues”. Comp. Biochem. Physiol. 34: 3—30. PMID 4988625.
- ^ Drozak, J., Veiga-da-Cunha, M., Vertommen, D., Stroobant, V. and Van Schaftingen, E. (2010). „Molecular identification of carnosine synthase as ATP-grasp domain-containing protein 1 (ATPGD1)”. J. Biol. Chem. 285: 9346—9356. PMID 20097752.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Carnosine+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
