Kodeinon reduktaza (NADPH)
Kodeinon reduktaza (NADPH) (EC 1.1.1.247, kodeinonska reduktaza (NADPH)) je enzim sa sistematskim imenom kodein:NADP+ oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Kodeinon reduktaza (NADPH) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.247 | ||||||||
| CAS broj | 153302-41-1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- kodein + NADP+ kodeinon + NADPH + H+
Kodeinonska reduktaza katalizuje reverzibilnu redukciju kodeinona do kodeina, koji je direktni prekurzor morfina u opijumskim biljkama maka, Papaver somniferum]].
Reference
уреди- ^ Lenz, R. & Zenk, M.H. (1995). „Stereoselective reduction of codeinone, the penultimate step during morphine biosynthesis in Papaver somniferum”. Tetrahedron Lett. 36: 2449—2452.
- ^ Lenz, R. & Zenk, M.H. (1995). „Purification and properties of codeinone reductase (NADPH) from Papaver somniferum cell cultures”. Eur. J. Biochem. 233: 132—139. PMID 7588736.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Codeinone+reductase+(NADPH) на US National Library of Medicine Medical Subject Headings (MeSH)
