Pankreasna elastaza II
Pankreasna elastaza II (EC 3.4.21.71, pankreasna elastaza 2) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Pankreasna elastaza II | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.71 | ||||||||
| CAS broj | 75603-19-9 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- Preferentno razlaganje veza: Leu-, Met- i Phe-. Dolazi do hidrolize elastina
Ova peptidaza iz S1 familije (tripsinske familije) se formira aktivacijom proelastaze II iz sisarskog pankreasa posredstvom tripsina.
Reference
уреди- ^ Fletcher, T.S., Shen, W.-F. and Largman, C. (1987). „Primary structure of human pancreatic elastase 2 determined by sequence analysis of the cloned mRNA”. Biochemistry. 26: 7256—7261. PMID 3427074.
- ^ Shirasu, Y., Yoshida, H., Matsuki, S., Takemura, K., Ikeda, N., Shimada, Y., Ozawa, T., Mikayama, T., Iijima, H., Ishida, A., Sato, Y., Tamai, Y., Tanaka, J. and Ikenaga, H. (1987). „Molecular cloning and expression in Escherichia coli of a cDNA encoding human pancreatic elastase 2”. J. Biochem. (Tokyo). 102: 1555—1563. PMID 2834346.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Pancreatic+elastase+II на US National Library of Medicine Medical Subject Headings (MeSH)
