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Tripsin (EC 3.4.21.4, alfa-tripsin, beta-tripsin, kokunaza, parenzim, parenzimol, triptar, tripur, pseudotripsin, tripcelim, sperm receptorska hidrolaza) je enzim.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju

Tripsin
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Identifikatori
EC broj3.4.21.4
CAS broj2594141
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBsum
Preferentno odvajanje: Arg-, Lys-

Jednolančani polipeptid goveđeg beta-tripsina se formira iz tripsinogena razlaganjem jedne peptidne veze.

ReferenceУреди

  1. ^ Huber, R. & Bode, W. (1978). „Structural basis of the activation and action of trypsin”. Acc. Chem. Res. 11: 114—122. 
  2. ^ Walsh, K.A. (1970). „Trypsinogens and trypsins of various species”. Methods Enzymol. 19: 41—63. 
  3. ^ Read, R.J., Brayer, G.D., Jurásek, L. and James, M.N.G. (1984). „Critical evaluation of comparative model building of Streptomyces griseus trypsin”. Biochemistry. 23: 6570—6575. PMID 6442164. 
  4. ^ Fiedler, F. (1987). „Effects of secondary interactions on the kinetics of peptide and peptide ester hydrolysis by tissue kallikrein and trypsin”. Eur. J. Biochem. 163: 303—312. PMID 3643848. 
  5. ^ Fletcher, T.S., Alhadeff, M., Craik, C.S. and Largman, C. (1987). „Isolation and characterization of a cDNA encoding rat cationic trypsinogen”. Biochemistry. 26: 3081—3086. PMID 3112218. 
  6. ^ Polgár, L. (1987). „Structure and function of serine proteases”. Ур.: Neuberger, A. and Brocklehurst, K. New Comprehensive Biochemistry: Hydrolytic Enzymes. 16. Amsterdam: Elsevier. стр. 159—200. 
  7. ^ Tani, T., Kawashima, I., Mita, K. and Takiguchi, Y. (1990). „Nucleotide sequence of the human pancreatic trypsinogen III cDNA”. Nucleic Acids Res. 18: 1631—1631. PMID 2326201. 

ЛитератураУреди

  • Polgár, L. (1987). „Structure and function of serine proteases”. Ур.: Neuberger, A. and Brocklehurst, K. New Comprehensive Biochemistry: Hydrolytic Enzymes. 16. Amsterdam: Elsevier. стр. 159—200. 

Spoljašnje vezeУреди