Bizmut subsalicilat
(преусмерено са Pepto-bismol)
Bizmut subsalicilat je organsko jedinjenje, koje sadrži 7 atoma ugljenika i ima molekulsku masu od 362,093 Da.[1][2][3]
![]() | |
![]() | |
Klinički podaci | |
---|---|
Prodajno ime | Bismatrol, Bismed, Bismuth caplets, Bismuth chewables |
Drugs.com | subsalicylate.html Monografija |
Način primene | Topikalno, oralno, sublingualno |
Identifikatori | |
CAS broj | 14882-18-9 ![]() |
ATC kod | A02BX05 (WHO), A02BX12 |
PubChem | CID 16682734 |
DrugBank | DB01294 ![]() |
ChemSpider | 17615374 ![]() |
KEGG | C07870 ![]() |
ChEBI | CHEBI:261649 ![]() |
ChEMBL | CHEMBL1120 ![]() |
Hemijski podaci | |
Formula | C7H5BiO4 |
Molarna masa | 362,093 |
| |
|
Osobine
уредиOsobina | Vrednost |
---|---|
Broj akceptora vodonika | 4 |
Broj donora vodonika | 1 |
Broj rotacionih veza | 0 |
Particioni koeficijent[4] (ALogP) | 1,0 |
Rastvorljivost[5] (logS, log(mol/L)) | 0,7 |
Polarna površina[6] (PSA, Å2) | 55,8 |
Reference
уреди- ^ Goldenberg MM, Honkomp LJ, Burrous SE, Castellion AW: Protective effect of Pepto-Bismol liquid on the gastric mucosa of rats. Gastroenterology. 1975 Sep;69(3):636-40. PMID 1158081
- ^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035—41. PMC 3013709 . PMID 21059682. doi:10.1093/nar/gkq1126.
- ^ David S. Wishart; Craig Knox; An Chi Guo; Dean Cheng; Savita Shrivastava; Dan Tzur; Bijaya Gautam; Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic acids research. 36 (Database issue): D901—6. PMC 2238889 . PMID 18048412. doi:10.1093/nar/gkm958.
- ^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
- ^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
- ^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.
Literatura
уреди- Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
- Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.
Spoljašnje veze
уреди
Molimo Vas, obratite pažnju na važno upozorenje u vezi sa temama iz oblasti medicine (zdravlja). |