Plazmin
Plazmin (EC 3.4.21.7, fibrinolizin, aktaza, serumska triptaza, trombolizin) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Plazmin | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifikatori | |||||||||
EC broj | 3.4.21.7 | ||||||||
CAS broj | 9001-90-5 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- Selektivno razlaganje: Lys- > Arg-; veća selektivnost od tripsina. Konvertuje fibrin u rastvorne produkte
Ovaj enzim se formira proteolizom iz plazminogena.
Reference
уреди- ^ Castellino, F.J. & Sodetz, J.M. (1976). „Rabbit plasminogen and plasmin isozymes”. Methods Enzymol. 45: 273—286. PMID 138065.
- ^ Castellino, F.J. & Powell, J.R. (1981). „Human plasminogen”. Methods Enzymol. 80: 365—378. PMID 6210827.
- ^ Robbins, K.C., Summaria, L. and Wohl, R.C. (1981). „Human plasmin”. Methods Enzymol. 80: 379—387. PMID 6210828.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.