Prolilna aminopeptidaza
Prolilna aminopeptidaza (EC 3.4.11.5, prolinska aminopeptidaza, Pro-X aminopeptidaza, citosolna aminopeptidaza V, prolinska iminopeptidaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Prolilna aminopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.11.5 | ||||||||
| CAS broj | 9025-40-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Odvajanje N-terminalnog prolina sa peptid
Za dejstvo ovog enzima je neophodan jon Mn2+.
Reference уреди
- ^ Sarid, S., Berger, A. and Katchalski, E. (1962). „Proline iminopeptidase. II. Purification and comparison with iminopeptidase (prolinase)”. J. Biol. Chem. 237: 2207—2212. PMID 14497218.
- ^ Nordwig, A. & Mayer, H. (1973). „The cleavage of prolyl peptidases by kidney peptidases”. Hoppe-Seyler's Z. Physiol. Chem. 354: 380—383. PMID 4803482.
- ^ Turzynski, A. & Mentlein, R. (1990). „Prolyl aminopeptidase from rat brain and kidney. Action on peptides and identification as leucyl aminopeptidase”. Eur. J. Biochem. 190: 509—515. PMID 2373079.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Prolyl+aminopeptidase на US National Library of Medicine Medical Subject Headings (MeSH)
