Trans-akonitrat 2-metiltransferaza
Trans-akonitrat 2-metiltransferaza (EC 2.1.1.144) je enzim sa sistematskim imenom S-adenozil-L-metionin:(E)-prop-1-en-1,2,3-trikarboksilat 2'-O-metiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Trans-akonitrat 2-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.144 | ||||||||
| CAS broj | 235107-12-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- S-adenozil-L-metionin + trans-akonitat S-adenozil-L-homocistein + (E)-3-(metoksikarbonil)pent-2-enedioat
Ovaj enzim takođe katalizuje formiranje metil monoestra cis-akonitata, izocitrata i citrata.
Reference уреди
- ^ Cai, H. & Clarke, S. (1999). „A novel methyltransferase catalyzes the esterification of trans-aconitate in Escherichia coli”. J. Biol. Chem. 274: 13470—13479. PMID 10224113.
- ^ Cai, H., Strouse, J., Dumlao, D., Jung, M.E. and Clarke, S. (2001). „Distinct reactions catalyzed by bacterial and yeast trans-aconitate methyltransferase”. Biochemistry. 40: 2210—2219. PMID 11329290.
- ^ Cai, H., Dumlao, D., Katz, J.E. and Clarke, S. (2001). „Identification of the gene and characterization of the activity of the trans-aconitate methyltransferase from Saccharomyces cerevisiae”. Biochemistry. 40: 13699—13709. PMID 11695919.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze уреди
- Trans-aconitate+2-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
