Skutelarin (enzim)
Skutelarin (EC 3.4.21.60, oksiuranus scutellatus protrombin-aktivirajuća proteinaza) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Skutelarin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.60 | ||||||||
| CAS broj | 93389-45-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Selektivno razlaganje veza Arg-Thr i Arg-Ile u protrombinu čime se formira trombin i dva neaktivna fragmenta
Ovaj enzim je izolovan iz venima zmije Tajpan (Oksiuranus scutellatus).
Reference уреди
- ^ Walker, F.J., Owen, W.G. and Esmon, C.T. (1980). „Characterization of the prothrombin activator from the venom of Oxyuranus scutellatus scutellatus (taipan venom)”. Biochemistry. 19: 1020—1023. PMID 6986908.
- ^ Speijer, H., Govers-Reimslag, J.W., Zwaal, R.F. and Rosing, J. (1986). „Prothrombin activation by an activator from the venom of Oxyuranus scutellatus (taipan snake)”. J. Biol. Chem. 261: 13258—13267. PMID 3531198.
Literatura уреди
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze уреди
- Scutelarin на US National Library of Medicine Medical Subject Headings (MeSH)
