Triptofan-tRNK ligaza

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Triptofan-tRNK ligaza
Triptofan-tRNK ligaza
Identifikatori
EC broj	6.1.1.2
CAS broj	9023-44-3
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Triptofan-tRNK ligaza (EC 6.1.1.2, triptofanil-tRNK sintetaza, L-triptofan-tRNKTrp ligaza (formira AMP), triptofanol-transfer ribonukleat sintetaza, triptofanil-transfer ribonukleinsko kiselinska sintetaza, triptofanil-transfer RNK sintetaza, triptofanil ribonukleinska sintetaza, triptofanil-transfer ribonukleinska sintetaza, triptofanil-tRNK sintaza, triptofanska translaza, TrpRS) je enzim sa sistematskim imenom L-triptofan:tRNKTrp ligaza (formira AMP).^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + L-triptofan + tRNK^Trp

\rightleftharpoons

AMP + difosfat + L-triptofil-tRNK^Trp

Reference уреди

^ Davie, E.W., Koningsberger, V.V. and Lipmann, F. (1956). „The isolation of a tryptophan-activating enzyme from pancreas”. Arch. Biochem. Biophys. 65: 21—28. PMID 13373404.
^ Preddie, E.C. (1969). „Tryptophanyl transfer ribonucleic acid synthetase from bovine pancreas. II. The chemically different subunits”. J. Biol. Chem. 244: 3958—3968. PMID 5805407.
^ Wong, K.K., Meister, A. and Moldave, K. (1959). „Enzymic formation of ribonucleic acid-amino acid from synthetic aminoacyladenylate and ribonucleic acid”. Biochim. Biophys. Acta. 36: 531—533. PMID 13845797.

Literatura уреди

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze уреди

Tryptophan---tRNA+ligase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Davie, E.W., Koningsberger, V.V. and Lipmann, F. (1956). „The isolation of a tryptophan-activating enzyme from pancreas”. Arch. Biochem. Biophys. 65: 21—28. PMID 13373404.

[2] Preddie, E.C. (1969). „Tryptophanyl transfer ribonucleic acid synthetase from bovine pancreas. II. The chemically different subunits”. J. Biol. Chem. 244: 3958—3968. PMID 5805407.

[3] Wong, K.K., Meister, A. and Moldave, K. (1959). „Enzymic formation of ribonucleic acid-amino acid from synthetic aminoacyladenylate and ribonucleic acid”. Biochim. Biophys. Acta. 36: 531—533. PMID 13845797.

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