Triptofan dehidrogenaza
Triptofan dehidrogenaza (EC 1.4.1.19, NAD(P)+-L-triptofan dehidrogenaza, L-triptofanska dehidrogenaza, L-Trp-dehidrogenaza, TDH) je enzim sa sistematskim imenom L-triptofan:NAD(P)+ oksidoreduktaza (deaminacija).[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Triptofan dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.4.1.19 | ||||||||
| CAS broj | 94047-13-9 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- L-triptofan + NAD(P)+ + H2O (indol-3-il)piruvat + NH3 + NAD(P)H + H+
Ovaj enzim aktivira Ca2+.
Reference
уреди- ^ Vackova, K., Mehta, A. and Kutacek, M. (1985). „Tryptophan aminotransferase and tryptophan dehydrogenase - activities in some cell compartments of spinach leaves - the effect of calcium-ions on tryptophan dehydrogenase”. Biol. Plant. 27: 154—158.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Tryptophan+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)
