Vanilat monooksigenaza
Vanilat monooksigenaza (EC 1.14.13.82, 4-hidroksi-3-metoksibenzoatna demetilaza, vanilatna demetilaza) je enzim sa sistematskim imenom vanilat:kiseonik oksidoreduktaza (demetilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju:
Vanilat monooksigenaza | |||||||||
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Identifikatori | |||||||||
EC broj | 1.14.13.82 | ||||||||
CAS broj | 39307-11-4 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- vanilat + O2 + NADH + H+ 3,4-dihidroksibenzoat + NAD+ + H2O + formaldehid
Ovaj enzim učestvuje u degradaciji vanilina kod Arthrobacter sp.
Reference
уреди- ^ Brunel, F. & Davison, J. (1988). „Cloning and sequencing of Pseudomonas genes encoding vanillate demethylase”. J. Bacteriol. 170: 4924—4930. PMID 3170489.
- ^ Priefert, H., Rabenhorst, J. and Steinbuchel, A. (1997). „Molecular characterization of genes of Pseudomonas sp. strain HR199 involved in bioconversion of vanillin to protocatechuate”. J. Bacteriol. 179: 2595—2607. PMID 9098058.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
уреди- Vanillate+monooxygenase на US National Library of Medicine Medical Subject Headings (MeSH)