Pankreasna elastaza
Pankreasna elastaza (EC 3.4.21.36, pankreatopeptidaza E, pankreasna elastaza I, elastaza, elaszim, serinska elastaza) je enzim.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Pankreasna elastaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.36 | ||||||||
| CAS broj | 2594837 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj enzim se formira aktivacijom proelastaze iz pankreasa sisara tripsinom.
Reference
uredi- ^ Shotton, D.M. (1970). „Elastase”. Methods Enzymol. 19: 113—140.
- ^ Harper, J.W., Cook, R.R., Roberts, C.J., McLaughlin, B.J. and Powers, J.C. (1984). „Active site mapping of the serine proteases human leukocyte elastase, cathepsin G, porcine pancreatic elastase, rat mast cell proteases I and II, bovine chymotrypsin Aα, and Staphylococcus aureus' protease V-8 using tripeptide thiobenzyl ester substrates”. Biochemistry. 23: 2995—3002. PMID 6380580.
- ^ Kawashima, I., Tani, T., Shimoda, K. and Takiguchi, Y. (1987). „Characterization of pancreatic elastase II cDNAs: two elastase II mRNAs are expressed in human pancreas”. DNA. 6: 163—172. PMID 3646943.
- ^ Bieth, J.G., Dirrig, S., Jung, M.-L., Boudier, C., Papamichael, E., Sakarellos, C. and Dimicoli, J.-L. (1989). „Investigation of the active center of rat pancreatic elastase”. Biochim. Biophys. Acta. 994: 64—74. PMID 2909256.
- ^ Bode, W., Meyer, E., Jr. and Powers, J.C. (1989). „Human leukocyte and porcine pancreatic elastase: X-ray crystal structures, mechanism, substrate specificity, and mechanism-based inhibitors”. Biochemistry. 28: 1951—1963. PMID 2655701.
Literatura
uredi- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
uredi- Pancreatic+elastase na US National Library of Medicine Medical Subject Headings (MeSH)
