Adenin fosforiboziltransferaza
Adenin fosforiboziltransferaza (EC 2.4.2.7, AMP pirofosforilaza, transfosforibozidaza, APRT, AMP-pirofosfat fosforiboziltransferaza, adenin fosforibozilpirofosfat transferaza, adenozin fosforiboziltransferaza, adenilat pirofosforilaza, adenilinska pirofosforilaza) je enzim sa sistematskim imenom AMP:difosfat fosfo-D-riboziltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Adenin fosforiboziltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.4.2.7 | ||||||||
CAS broj | 9027-80-9 | ||||||||
Baze podataka | |||||||||
IntEnz | IntEnz pregled | ||||||||
BRENDA | BRENDA pristup | ||||||||
ExPASy | NiceZyme pregled | ||||||||
KEGG | KEGG pristup | ||||||||
MetaCyc | metabolički put | ||||||||
PRIAM | profil | ||||||||
Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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5-Amino-4-imidazolekarboksamid može da zameni adenin.
Reference
уреди- ^ Flaks, J.G., Erwin, M.J. and Buchanan, J.M. (1957). „Biosynthesis of the purines. XVI. The synthesis of adenosine 5′-phosphate and 5-amino-4-imidazolecarboxamide ribotide by a nucleotide pyrophosphorylase”. J. Biol. Chem. 228: 201—213. PMID 13475309.
- ^ Kornberg, A., Lieberman, I. and Simms, E.S. (1955). „Enzymatic synthesis of purine nucleotides”. J. Biol. Chem. 215: 417—427. PMID 14392175.
- ^ Lukens, L.N. & Herrington, K.A. (1957). „Enzymic formation of 6-mercaptopurine ribotide”. Biochim. Biophys. Acta. 24: 432—433. PMID 13436452.
Literatura
уреди- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
уреди- Adenine+phosphoribosyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)