Laktaza (EC 3.2.1.108, laktaza-florizinska hidrolaza) je enzim sa sistematskim imenom laktoza galaktohidrolaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju

Laktaza
Laktaza tetramer, E.Coli
Identifikatori
EC broj3.2.1.108
CAS broj2604851
Baze podataka
IntEnzIntEnz pregled
BRENDABRENDA pristup
ExPASyNiceZyme pregled
KEGGKEGG pristup
MetaCycmetabolički put
PRIAMprofil
Strukture PBPRCSB PDB PDBe PDBj PDBsum
laktoza + H2O D-galaktoza + D-glukoza

Enzim iz intestinalne sluznice je izolovan kao kompleks koji takođe katalizuje reakciju enzima EC 3.2.1.62, glikozilkeramidaza.

Reference

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  1. ^ Lorenz-Meyer, H., Blum, A.L., Haemmerli, H.P. and Semenza, G. (1972). „A second enzyme defect in acquired lactase deficiency: lack of small-intestinal phlorizin-hydrolase”. Eur. J. Clin. Invest. 2: 326—331. PMID 5082068. 
  2. ^ Ramaswamay, S. & Radhakrishnan, A.N. (1975). „Lactase-phlorizin hydrolase complex from monkey small intestine. Purification, properties and evidence for two catalytic sites”. Biochim. Biophys. Acta. 403: 446—455. PMID 810166. 
  3. ^ Schlegel-Haueter, S., Hore, P., Kerry, K.R. and Semenza, G. (1972). „The preparation of lactase and glucoamylase of rat small intestine”. Biochim. Biophys. Acta. 258: 506—519. PMID 5010299. 
  4. ^ Skovbjerg, H., Norén, O., Sjöström, H., Danielsen, E.M. and Enevoldsen, B.S. (1982). „Further characterization of intestinal lactase/phlorizin hydrolase”. Biochim. Biophys. Acta. 707: 89—97. PMID 6814489. 
  5. ^ Skovbjerg, H., Sjöström, H. and Norén, O. (1981). „Purification and characterization of amphiphilic lactase-phlorizin hydrolase from human small-intestine”. Eur. J. Biochem. 114: 653—661. PMID 6786877. 
  6. ^ Asp, N.G., Dahlqvist, A. and Koldovský, O. (1969). „Human small-intestinal β-galactosidases. Separation and characterization of one lactase and one hetero β-galactosidase”. Biochem. J. 114: 351—359. PMID 5822067. 

Literatura

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Spoljašnje veze

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  • Lactase na US National Library of Medicine Medical Subject Headings (MeSH)